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ONLINE GLOSSARY

Taber’s Online (Cyclopedic Medical Dictionary)

THE HISTORY OF CRIXIVAN

When Merck launched its AIDS research program in January 1987, the pressure was already mounting from all sides. A protease inhibitor was not going to be an easy drug to develop—that much was known...
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CRIXIVAN^® (indinavir sulfate) in combination with other antiretroviral agents is indicated for the treatment of HIV infection. This indication is based on 2 clinical trials of approximately 1 year’s duration that demonstrated (1) a reduction in the risk of AIDS-defining illness or death and (2) a prolonged suppression of HIV RNA.

CRIXIVAN:

• Does not cure HIV infection
• Does not reduce the transmission of HIV
• Should only be taken in combination with other drugs for HIV

CRIXIVAN is contraindicated in patients with clinically significant hypersensitivity to any of its components.

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