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Discuss all medications you are taking or plan to take with your doctor, including nonprescription medicines, herbal products, or dietary supplements. Taking CRIXIVAN with any products containing St. John’s wort, an herbal supplement, is not recommended because it has been shown to decrease CRIXIVAN levels and may lead to increased viral load and possible resistance to CRIXIVAN or cross-resistance to other antiretroviral drugs.
If you take Viagra® (sildenafil), Cialis® (tadalafil), or Levitra® (vardenafil) with CRIXIVAN, you may be at increased risk of side effects of these medications, such as low blood pressure, visual changes, and penile erection lasting more than 4 hours. If an erection lasts longer than 4 hours, you should seek immediate medical assistance to avoid permanent damage to your penis.
| Cordarone® (amiodarone) |
| Ergot medications (eg, Wigraine®, Cafergot®, D.H.E. 45, Migranal®, Ergotrate®, Methergine®) |
| Halcion® (triazolam) |
| Hismanal® (astemizole) |
| Mevacor® (lovastatin) |
| Orap® (pimozide) |
| Propulsid® (cisapride) |
| Reyataz™ (atazanavir) |
| Rifadin®, Rifamate®, Rifater®, Rimactane® (rifampin) |
| Versed® (midazolam) |
| Zocor® (simvastatin) |
| Bactrim®/Septra® (trimethoprim/sulfamethoxazole) |
| Biaxin® (clarithromycin) |
| Crestor® (rosuvastatin) |
| Diflucan® (fluconazole) |
| Epivir® (lamivudine, 3TC) |
| Isoniazid® (INH) |
| Lipitor® (atorvastatin) * |
| Methadone |
| Mycobutin® (rifabutin) * |
| Nizoral® (ketoconazole) * |
| Ortho-Novum 1/35® (oral contraceptive) |
| Rescriptor® (delavirdine)* |
| Retrovir® (zidovudine) |
| Sporanox® (itraconazole) * |
| Sustiva® (efavirenz) * |
| Tagamet® (cimetidine) |
| Videx® (didanosine) * |
| Zerit® (stavudine, d4T) |
May require special instruction from your doctor, including dose modification.
Tell your doctor if you are taking calcium channel blockers (eg, amlodipine, felodipine), antiarrhythmics (eg, quinidine), anticonvulsants (eg, carbamazepine, phenobarbital, phenytoin), or steroids (eg, dexamethasone).
Talk to your doctor about any medications you are taking or plan to take.
For additional information about CRIXIVAN, please read the Patient Product Information.
The physician Prescribing Information is also available.
These brands are the trademarks of their respective owners and are not trademarks of MERCK & CO., Inc. ZOCOR, MEVACOR, and CRIXIVAN are registered trademarks of MERCK & CO., Inc.
